Milo , Networks Network Motifs : Simple Building Blocks of Complex
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Network motifs: simple building blocks of complex networks.
Complex networks are studied across many fields of science. To uncover their structural design principles, we defined "network motifs," patterns of interconnections occurring in complex networks at numbers that are significantly higher than those in randomized networks. We found such motifs in networks from biochemistry, neurobiology, ecology, and engineering. The motifs shared by ecological fo...
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Biological and technological networks contain patterns, termed network motifs, which occur far more often than in randomized networks. Network motifs were suggested to be elementary building blocks that carry out key functions in the network. It is of interest to understand how network motifs combine to form larger structures. To address this, we present a systematic approach to define "motif g...
متن کاملComment on "Network motifs: simple building blocks of complex networks" and "Superfamilies of evolved and designed networks".
Recently, excitement has surrounded the application of null-hypothesis approaches for identifying evolutionary design principles in biological, technological, and social networks (1–13) and for classifying diverse networks into distinctive superfamilies (2). Here, we argue that the basic method suggested by Milo et al. (1, 2) often has limitations in identifying evolutionary design principles. ...
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